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Using a 1:10 solution of sodium hypochlorite is considered the appropriate method for cleaning a blood spill in the laboratory due to its effectiveness as a disinfectant. Sodium hypochlorite is a common bleach that can effectively kill a wide range of pathogens, including viruses and bacteria, thereby minimizing the risk of infection and contamination. The 1:10 dilution is specifically recommended because it provides a strong enough concentration to be effective without being overly harsh on surfaces.

While other methods, such as using tissue paper or bleach wipes, might seem convenient, they do not provide the same level of disinfection that a sodium hypochlorite solution does. Wiping with tissue paper simply spreads the contamination and does not properly disinfect the area. Similarly, bleach wipes may not meet the required concentration for effective disinfection against bloodborne pathogens, depending on their formulation. Running water over the spill is insufficient, as it does not disinfect the area and may further spread the contamination. Therefore, the choice of using a 1:10 sodium hypochlorite solution is essential for ensuring that the workspace remains safe and free from infectious agents.